NGEC Workshop 2010
The complete Abstract Booklet can be downloaded in the Attachment section below.
2010 Keynote Speakers
Dr. Bruce Torbett
The Scripps Research Institute
Department of Molecular and Experimental Medicine
10550 North Torrey Pines Road, MEM-131
La Jolla, CA 92037
Email: betorbett <at> scripps <dot> edu
Phone: (858) 784-9123
Fax: (858) 784-7714
Bruce E. Torbett received his Ph.D. in Cellular, Molecular, and Developmental Biology from the University of California, Los Angeles, and completed his postdoctoral research at The Scripps Research Institute, La Jolla, California. He is currently an Associate Professor in the Departments of Molecular and Experimental Medicine and Immunology Microbial Sciences, The Scripps Research Institute and in the Department of Pathology, School of Medicine, University of California, San Diego, California.
Dr. Torbett studies HIV-1 vector entry and gene delivery to human hematopoietic cells, myeloid development, and co-evolution of HIV-1 protease and its substrate, gag-pol. He and his group’s have made numerous contributions to these fields, including the demonstration that HIV vectors target human hematopoietic stem cells, disruption of the expression of the HIV-1 entry portal, CCR5, through gene delivery protects and allows expansion of T cells in the presence of an ongoing infection, and the regulatory role of the transcription factor, PU.1, in myeloid differentiation.
Dr. Toni Cathomen
Hannover Medical School
Experimental Hematology, OE 6960
30625 Hannover, Germany
Email: cathomen <dot> toni <at> mh-hannover <dot> de
Phone: +49 511 532 5170
Fax: +49 511 532 5121
Toni Cathomen received his Ph.D. in Molecular Biology from the University of Zurich, Switzerland, and conducted postdoctoral research in Zurich and at the Salk Institute for Biological Studies in San Diego, CA. He was Assistant Professor of Molecular Virology at Charité Medical School in Berlin and has recently been appointed to Associate Professor of Genome Engineering at Hannover Medical School, Germany.
Dr. Cathomen’s main interest is the characterization of the mechanisms that regulate the repair of DNA double-strand breaks (DSBs) and the exploitation of this knowledge to specifically alter the genetic makeup of cells. His rational genome engineering approach is mainly based on the use of zinc-finger nucleases (ZFNs), which can be designed to insert a site-specific DSB in a given gene of interest. The lab has made seminal contributions to the field by applying protein engineering technologies to improve the specificity of these artificial nucleases. The long-term goal of his lab is to introduce specific alterations in the genome of pluripotent and multipotent stem cells to improve our understanding of DNA repair in somatic stem cells and to develop novel treatment options for patients suffering from hereditary disorders.
|2010 Abstract Booklet (PDF)||628.23 KB|